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Research: Rethinking mastitis treatment to improve costs and health

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New research from the College of Veterinary Medicine at Michigan State University has found that dairy producers overtreat cows diagnosed with non-severe cases of clinical mastitis, which increases farm costs and contributes to a significant loss of milk due to antibiotic treatment.

Pamela Ruegg, the David J. Ellis Chair in Antimicrobial Resistance and professor in the Department of Large Animal Clinical Sciences, estimates the direct costs of treatment could be reduced by $65.20 per case if the minimum labeled durations are used, which she said provides the same health outcomes as current practices. The cost of mastitis to the U.S. dairy industry is approximately $110 per cow per year — and that dollar amount increases annually. 

In dairy cows, mastitis is the inflammation of mammary glands in the udder, usually caused by a bacterial infection that leads to decreased quantity and quality of milk. Milk produced by cows while they’re being treated with antibiotics must be discarded, as well as the milk produced after treatment during the withholding period — usually three to four days after the last treatment has been given.

Published in the Journal of Dairy Science, Ruegg analyzed non-severe cases of clinical mastitis for approximately 50,000 cows on 37 commercial dairy farms in Wisconsin. She found that milk discarded because of the antibiotic treatment represents at least 53 percent and up to 80 percent of total direct costs for each day of treatment. Mastitis is an expensive disease — Ruegg said because cows now produce almost twice as much milk since she started practicing in 1984, the same treatment protocol today costs approximately 40% more.

The bottom line: Ruegg found that for routine treatments, following the minimum labelled duration for mastitis treatment drugs is critical to farm cost savings and productivity, as well as maintaining animal and human health.

Image by Toa55, Shutterstock

“Our work indicates that we need to take a hard look at duration of treatment, and unless you can justify improved clinical outcomes, we should treat using the minimum duration listed on product labels, and for shorter durations,” Ruegg said.

“With that, there’s both a financial savings for the producer, and there’s a human health benefit because we’re putting less antimicrobials into our ecosystems. There are benefits for society, and guess what? You’ll have the same outcomes.”

The opportunity to save on the costs of treatment and regain revenue from less discarded milk is hard to ignore for producers who are already facing steep fiscal challenges. Dairy producers in the U.S. are battling against federal milk pricing regulations and pandemic aftermath, losing on average more than $6 per hundredweight (milk sales unit) on farms of more than 50 cows.

And mastitis isn’t going anywhere, Ruegg said.

“The proportion of cows with clinical mastitis isn’t going down. At best, it’s stable, and at worst, it’s increasing, probably because of environmental pathogens that tend to cause larger inflammatory responses,” she said.

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